Garcinia cambogia for weight loss safety

Garcinia cambogia for weight loss safety
Garcinia Cambogia Customer Reviews For Weight Loss The fruit of the Garcinia cambogia plant is packed full of beneficial components including antioxidants.

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Analyses Performed

Must-see Statistic

Unconventional Wisdom

Labdoor analyzed 29 best-selling G. cambogia herbal supplements in the United States, measuring levels of the key active ingredient, hydroxycitric acid (HCA), as well as heavy metal content (antimony, arsenic, bismuth, cadmium, and silver).

Actual hydroxycitric acid (HCA) content ranged from -99.5% to +32.2% vs. the products stated label claims.

All products in this report were screened by Inductively Coupled Plasma (ICP)-based techniques for the presence of heavy metals. Samples of each product passed all six heavy metals assays, indicating that samples contained under 1 PPM (part per million) each of arsenic, lead, cadmium, bismuth, antimony, and silver compounds.

Labdoor's Nutritional Value calculations are largely based on macronutrient ratios, with added sugars, sodium, and cholesterol being penalized in this rating. Most Garcinia supplements recorded low values across the board here.

Labdoor’s Ingredient Safety calculations are based on two key factors: active ingredient dose as well as presence and severity of key heavy metals and added excipients.

HCA, the primary active ingredient responsible for G. cambogia’s weight-loss effects, is suggested to work primarily by reducing de novo lipogenesis, the process during which carbohydrates are converted into fat (via the competitive inhibition of the enzyme citric acid lysase). Studies have also suggested that HCA may help suppress appetite (by regulating levels of the neurotransmitter serotonin, which plays a role in satiety.) These claims have been replicated in animal studies.

Garcinia Cambogia Weight-Loss Pill Is No Miracle

The claims make this supplement tempting, but they're untrue

Garcinia cambogia is hot.

Miracle fruit, on the other hand, is considered completely safe to eat, with no known side effects, other than the “flavor tripping” ones, of course.

Nearly a million Americans each month Google this supposed weight-loss supplement. They're looking for reviews on garcinia cambogia's effectiveness, what kind of side effects it causes, and where they can buy it. My mom recently bought a bottle of the pills at Costco because she saw a segment about garcinia cambogia on a TV show.

Manufacturers claim that garcinia cambogia boosts weight loss by, among other things, "slowing the body's ability to absorb fat," "replacing fat with toned muscles," and even improving your mood and suppressing "the drive to react to stressful situations with food." How, you may ask? It's mostly pinned on hydroxycitric acid (HCA), a substance found in garcinia cambogia that appears to inhibit an enzyme called citrate lyase and interferes with fatty acid metabolism.

“HCA does do that—but in a petri dish," says Steven Heymsfield, M.D., the former head of the Pennington Biomedical Research Center in Baton Rouge, La. "Converting that to actual weight loss in humans would take 1,000 steps beyond that," he says.

Back in 1998, Heymsfield published the first randomized controlled trial on the effectiveness of garcinia cambogia, in the Journal of the American Medical Association. He found no weight-loss benefits. Heymsfield, who continues to study the topic of weight-loss supplements at Pennington, says that about a dozen negative studies have since been published about garcinia cambogia. But that has not stopped marketers of the supplement, he says, from “weaving a story with obscure facts. Maybe each fragment has some validity, but if you wind it together it makes no sense at all.”

His original study, conducted by Columbia University’s Obesity Research Center, looked at 135 overweight men and women age 18 to 65; about half were given garcinia cambogia and the other half a placebo three times a day before meals.

Garcinia Ultra Pure is produced in the United States in a state-of-the-art cGMP certified manufacturing facility that conforms to the tested grade strength and purity of USP quality standards and is manufactured under the strict guidelines.

You get fat because of unhealthy habits that cause you to stay bloated forever, unless you do something about it.

Both groups ate a high-fiber diet and returned for evaluation every two weeks. At the end of the 12-week trial, there were no important differences in weight loss between the two groups.

A review of 12 trials involving garcinia products published in the Journal of Obesity in 2011 came to the same conclusion. Another study by researchers at Victoria University in Melbourne, Australia, and published in 2013 in the journal Complementary Therapies in Medicine found that overall the evidence for garcinia cambogia was “not compelling.”

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As for garcinia cambogia's side effects, controlled studies and animal studies have found very few, although Heymsfield says, “I don’t think it’s 100 percent safe.”

In 2009 the Food and Drug Administration warned consumers about Hydroxycut, a product line containing garcinia cambogia and several other ingredients, based on serious reports of health problems, including jaundice, elevated liver enzymes, liver damage requiring a transplant, and one death from liver failure. The FDA said it was unable to determine exactly which ingredients were associated with the liver injuries. (Hydroxycut's manufacturer, Iovate Health Sciences, withdrew the products, though it has since returned a reformulated product to the market containing no garcinia cambogia.)

“Being obese is difficult because only some of it is related to self-control,” Heymsfield says. “And it’s not easy to lose weight in our environment. Just preventing further weight gain is an accomplishment for some people.” The biggest problem with garcinia cambogia, Heymsfield says, besides being a waste of money, is that it distracts people from concentrating on the important things when it comes to weight loss: increasing your activity level and eating a healthier diet.

As for my mom, she returned the bottle to Costco and got her $20 back.

Garcinia Cambogia

On This Page

This fact sheet provides basic information about garcinia cambogia—common names, usefulness and safety, and resources for more information.

Common Names: garcinia cambogia, garcinia, Malabar tamarind, brindle berry

Background

  • Garcinia cambogia (Malabar tamarind) is native to India and Southeast Asia.

    If you're struggling to lose the weight, enlist the help of your doctor and a dietitian.

    The rind of its fruit is used to flavor fish curries and preserve food.

  • The rind contains a chemical called hydroxycitric acid (HCA), which has been studied for its effect on appetite. Garcinia cambogia supplements with HCA are marketed for weight loss.
  • Garcinia cambogia has also been used as a dietary supplement for rheumatism, intestinal problems, and other conditions.
  • Garcinia cambogia is made into a tea, capsules, extracts, tablets, and lotion.

How Much Do We Know?

  • Garcinia cambogia has been studied for weight loss, but there aren’t a lot of recent, reliable studies on its effectiveness.

What Have We Learned?

  • There’s no convincing evidence that garcinia cambogia will help you lose weight or control cholesterol.
  • In a very small study, women who were overweight were given garcinia cambogia extract or a placebo for 60 days. Triglyceride levels of the participants getting garcinia cambogia decreased by almost one-third. Triglycerides are a type of fat in blood and high levels may raise a person’s risk of developing heart disease. The participants’ HDL (the “good” cholesterol), LDL (the “bad” cholesterol), total cholesterol, and body weight didn’t change.
  • In another study, people who were overweight were given either garcinia cambogia extract, soy leaf extract, or a placebo. After 10 weeks, none of the supplements promoted weight loss or lowered total cholesterol.

What Do We Know About Safety?

  • Taking garcinia cambogia for short periods (12 weeks or less) appears safe for most people.

Keep in Mind

  • Tell all your health care providers about any complementary or integrative health approaches you use.

    In order to be safe, you might want to consider buying it from the official online store.

    Give them a full picture of what you do to manage your health. This will help ensure coordinated and safe care.

Key References

  • Astell KJ, Mathai ML, Su XQ. Plant extracts with appetite suppressing properties for body weight control: a systematic review of double blind randomized controlled clinical trials.Complementary Therapies in Medicine. 2013;21(4):407-416.
  • Garcinia. Natural Medicines Web site. Accessed at naturalmedicines.therapeuticresearch.com on April 10, 2015. [Database subscription].
  • Greenway F. Garcinia. In: Coates PM, Betz JM, Blackman MR, et al., eds. Encyclopedia of Dietary Supplements. 2nd ed. New York, NY: Informa Healthcare; 2010:307-313.
  • Kim JE, Jeon SM, Park KH, et al. Does Glycine max leaves or Garcinia cambogia promote weight-loss or lower plasma cholesterol in overweight individuals: a randomized control trial. Nutrition Journal. 2011;10:94.
  • Lopez AM, Kornegay J, Hendrickson RG. Serotonin toxicity associated with Garcinia cambogia over-the-counter supplement. Journal of Medical Toxicology. 2014;10(4):399-401.
  • Semwal RB, Semwal DK, Vermaak I, et al. A comprehensive scientific overview of Garcinia cambogia. Fitoterapia. 2015;102:134-148.
  • Vasques CA, Schneider R, Klein-Júnior LC, et al. Hypolipemic effect of Garcinia cambogia in obese women.Phytotherapy Research. 2014;28(6):887-891.

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This page last modified September 24, 2017

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