Garcinia cambogia results in one month

Garcinia cambogia results in one month
A lot of these brands actually offer garcinia cambogia free trials but before you jump on the bandwagon of natural weight loss, you have to equip yourself with the basic knowledge about what the supplement is, what it does, and how to choose the best quality brands for your body.

Garcinia cambogia results in one month

Don't Buy Garcinia Cambogia Until You Know You Are Getting One That Works

When you want to lose weight, the safest way to go is the natural way. However, results can sometimes take too long that people would rather turn to supplements made with harsh chemicals and even surgery to get the body that they want overnight. Indeed, losing weight can be such a challenge, especially if you have a very busy lifestyle.

With scientists and the general media raving, one of the most popular NATURAL weight loss solutions today is garcinia cambogia extract dietary supplements. An exciting new breakthrough in the weight loss industry, it is considered to be mother nature's simple answer to losing weight.

One of the recommended brands of garcinia cambogia is Garcinia Cambogia Extra . Made with 100% natural and 100% pure ingredients, Garcinia Cambogia Extra gives you fast and effective results even WITHOUT DIET or EXERCISE!! Making you lose weight in 3 ways, Garcinia Cambogia Extra is the perfect solution to a healthier and slimmer body.

Overview of Garcinia Cambogia Extra

Garcinia Cambogia Extra manufactured in an FDA registered, cGMP certified laboratory, ensuring you that they are up to par with the high standards in manufacturing. Safe and effective, Garcinia Cambogia Extra promises results AND delivers.

Unlike other garcinia cambogia extract products that are filled with other ingredients, Garcinia Cambogia Extract is 100% PURE – which means it has NO fillers, NO binders, and NO artificial chemicals! These all-natural veggie capsules meet every criteria of an effective and fast-acting garcinia cambogia product:

  • Contains 60% HCA (Hydroxycitric Acid)- the needed percentage that makes garcinia cambogia effective in weight loss
  • Its recommended dose is 500mg before each meal – the needed dose is from 1500-3000mg ever day
  • Garcinia Cambogia Extra is made of 100% pure HCA and 100% natural ingredients with NO calcium, NO binders, NO fillers, and NO additives
  • All of their products are made in FDA registered laboratories and cGMP certified labs – assuring you that each bottle meets the standards of quality

Producing truly effective and pure garcinia cambogia extract capsules, Garcinia Cambogia Extra promises 100% Satisfaction and 30-Days Money Back Guarantee!

How Does Garcinia Cambogia Extra Work?

Garcinia Cambogia is a tropical natural fruit that is dubbed as a superfruit. The extract in the capsules is taken from the rind, where there are great amounts of HCA (Hydroxycitric Acid) – the key ingredient to making you lose weight. It works in a triple-action powerful combination:

1. Inhibits your appetite by telling your brain that you are already full while also making your feel fuller longer.

2. Blocks fat from being formed in the body by preventing the citrate lyase from turning your carbohydrates into fat. Instead it is turned into energy.

3. Boosts serotonin levels in your brain, which makes you feel better by improving your moods and regulating sleep – decreasing your need for emotional eating.

This triple-action formula is the powerful combination that gives garcinia cambogia its effective weight loss properties.

Garcinia Cambogia Extra Benefits

Aside from the 3 main ways that Garcinia Cambogia Extra help you lose weight, here are its other great benefits:

  • Lowers the level of bad cholesterol in your body
  • Manages the stress hormone cortisol, helping emotional eaters from food cravings
  • Attacks your belly fat

Moves toward glycogen – which helps you burn more fat

Decreases your urge to consume more calories

Because Garcinia Cambogia Extra is made with an all-natural fruit, there are NO SIDE EFFECTS!

You get to lose weight and body fat even WITHOUT DIET NOR EXERCISE! Compared to others who did not take garcinia cambogia, users lost 2-3 times more weight – and that's without changing a thing to their lifestyle! Just the perfect solution for busy bodies.

Ordering Garcinia Cambogia Extra

Because of the popularity of the product, Garcinia Cambogia Extra is struggling to keep their supply in stock. You can visit their safe and secure website to get your hands on any of their product packages. Currently, there are 3 to choose from:

  • Order 1 bottle (1 Month Supply) for $49.95! Lose up to 10 lbs
  • Order 2 bottles and get 1 bottle FREE($33.00 each, $99.95 total)! Lose up to 20 lbs
  • Garcinia Cambogia Extra's BEST SELLING PACKAGE. Order 3 bottles and get 2 bottles FREE ($29.00 each, $149.95 total)! Lose up to 30 lbs

ALL ORDERS come with 30-DAY MONEY BACK GUARANTEE! So, feel confident that you will lose weight, or your money back!

http://thetopweightlosspills.com.au is a great place to tons of diet supplement reviews and info on related topics.

Simply go to Garcinia Cambogia Extra's official website , choose a package, pay for your bottles and everything will be shipped quick! Safe, fast, and effective, ORDER your Garcinia Cambogia Extra before supplies run out!

Garcinia cambogia results in one month

Garcinia Cambogia: The Newest, Fastest Fat Burner?

If you’ve been trying to lose weight, you’ve most likely heard of garcinia cambogia – a fruit believed to hold the very key to healthy weight loss. If you’ve never considered using garcinia cambogia extract supplements for weight loss before, then it’s about time you should.

Garcinia cambogia is a tropical fruit found in the countries of Southeast Asia. People who live in the region have long used this incredible tiny fruit to make dishes more filling. Western scientists who encountered the fruit, decided to study its weight loss abilities and discovered that the rind contains massive amounts of HCA – which is short for Hydroxycitric Acid.

HCA is the very key ingredient why garcinia cambogia supplements are making a massive name in the weight loss industry today. HCA is known to suppress appetite and prevent your body from making fat tissues – leading to fast and effective weight loss done through the most natural and safest way possible.

Why Is Garcinia Cambogia So Popular?

In the world of natural weight loss solutions, no other name surpasses garcinia cambogia as the most recommended and most effective natural weight loss supplement in the market.

Garcinia cambogia came into national consciousness through the efforts of Dr. Oz – the most famous doctor on TV today. Immensely impressed by recent scientific research, he dubbed garcinia cambogia as the “holy grail” to beat weight gain.

Immediately after featuring the supplement in his show, tens of thousands of individuals around the country decided to use the supplement to combat excess weight and keep the weight away.

And because it’s 100% all-natural and truly effective in weight loss even without the help of diet and exercise, garcinia cambogia has become the best selling and most recommended natural weight loss supplement in the industry today.

How Garcinia Cambogia Extract Helps for Weight Loss

Garcinia cambogia supplements work through the mechanisms of HCA – the very key ingredient that makes the extract a powerful weight loss solution.

It somehow uses your own body’s chemicals to combat weight gain, giving you natural and healthy weight loss from the inside out.

HCA works through two main mechanisms: Suppression of Appetite and Fat Production Prevention.

1. Suppression of Appetite

One of the main reasons why people can’t seem to lose weight is because they can’t control what they eat, and the volume of food that they eat. It’s a sad fact that appetite is one of the hardest things to control.

HCA helps you lower your food consumption by making your body feel full even when you’ve only had little to eat. This means you get to say goodbye to cravings such as sweets and salty foods, say goodbye to emotional and binge eating and say hello to smaller portions each and every time.

HCA helps you eat only the amount of food that your body needs, and nothing more – helping you lose excess weight and maintain a healthy daily calorie intake.

2. Fat Production Prevention

Whenever you eat carbohydrates, your body converts them into energy. Now when you don’t use this energy, a certain enzyme named citrate lyase converts these carbohydrates into fat tissues – giving you not just weight gain, but nasty fat tissues that go to your stomach, arms, thighs, and all the other parts of the body that accumulate fat.

When you take HCA, this enzyme will no longer work. HCA inhibits citrate lyase and the entire process of fat production will no longer exist – giving you effective fat production prevention done in the most natural way possible.

Helping you ward off cravings and fat production, garcinia cambogia is an all-natural supplement giving your body natural methods to combat excess fat and weight.

Studies that Prove Garcinia Cambogia’s Effectiveness

Several studies on garcinia cambogia can be found at the website of the US National Library of Medicine National Institutes of Health.

One of these studies was done by Downs, BW, Bagchi M, and others in November of 2005.

The study, entitled “ Bioefficacy of a novel calcium-potassium salt of HCA ,” proved that HCA, together with potassium and calcium, results to increased serotonin availability, reduced appetite, increased fat oxidation, increased blood lipid levels, reduced body weight, and the modulation of a number of obesity regulatory genes.

Another study was done on May 2004 – Preuss, HG, and others conducted a randomized, double-blind, placebo-controlled human clinical study in Elluru, India over the period of 8 weeks.

But you shouldn't use it if you're already on a prescription for your cholesterol.

This feature differentiates it from other weight reducing supplements that require a specific diet plan tow work effectively.

The subjects were 60 moderately-obese individuals aged 21 to 50 years old.

This group of people were divided into 3: Group 1 took HCA, Group 2 took niacin-bound HCA, and Group 3 took placebo pills.

At the end of the study, the researchers discovered that both Groups 1 and 2 had reduced body weight, reduced body mass index, reduced food intake, and reduced total cholesterol.

Preuss and others then concluded that optimal doses of HCA can serve as a potentially safe and effective weight loss formula that can facilitate effective reductions in both excess body weight and body mass index.

Does It Have Any Side Effects?

There have been reports of nausea and stomach upsets from actual users, but severe side effects have not occurred. Users who do experience side effects may have used products that contained other ingredients aside from HCA and/or potassium and calcium.

Because garcinia cambogia is so popular, literally tens of thousands of garcinia cambogia products have popped up in the market. And because you don’t need to have a prescription to buy one, it’s so easy to purchase these supplements from just about anywhere and from anyone.

It’s very important that you equip yourself with the knowledge and qualifications of what a top quality and effective garcinia cambogia product is so you know you’re getting an authentic product that’s safe and most of all, effective.

Are Garcinia Cambogia Products Made the Same?

The answer to this is no. There are literally thousands of garcinia cambogia products out there but only a small number really do stand out in the market.

Dr. Oz emphasized the importance of certain requirements of a top quality garcinia cambogia supplement. When you look for a product, the following qualifications are a definite must:

  • The product must contain at least 50% pure HCA concentration
  • It must have the label “HCA” or “Garcinia Cambogia” on the bottle
  • It must contain 100% all natural ingredients
  • Each capsule must have at least 500mg of dosage
  • The product must be made in FDA-registered and GMP-certified laboratories

If a certain garcinia cambogia brand adheres to these requirements, then you know you have a top quality product that’s safe, healthy, and truly effective.

Where to Buy Garcinia Cambogia

The supplements we recommend here are available through retail stores or exclusively online. One of our bestselling and top recommended products is Garcinia Cambogia Extra , satisfying thousands of users!

Meeting all these qualifications is Garcinia Cambogia Extra – is made in FDA registered and cGMP-certified laboratories, ensuring you that each and every capsule satisfies the manufacturing, testing, and quality assurance of Good Manufacturing Practices.

With 60% HCA in every dosage, Garcinia Cambogia Extra is one the top garcinia cambogia product to try today.

They are only available through their official website, so head to Garcinia Cambogia Extra and choose from these 3 packages:

Worldwide Shipping Available!

  1. Order 1 bottle (1 Month Supply) for $49.95! Lose up to 10 lbs
  2. Order 2 bottles and get 1 bottle FREE($33.00 each, $99.95 total)! Lose up to 20 lbs
  3. Garcinia Cambogia Extra’s BEST SELLING PACKAGE. Order 3 bottles and get 2 bottles FREE ($29.00 each, $149.95 total)! Lose up to 30 lbs

ALL ORDERS come with 30-DAY MONEY BACK GUARANTEE! Garcinia cambogia is a dosage-based supplement, which means the more you use, the more weight you’ll lose. Choose from these 3 package options and start your weight loss journey today.

Garcinia Cambogia Review: What You Need To Know

What's Inside This Guide

What’s all the fuss about? Well, this fruit rind extract has been touted as a revolutionary way to lose fat, tone up and suppress those cravings all in one natural supplement. With virtually no side effects, not like the awful buzz of too much caffeine or the nauseous feeling that many appetite suppressants can bring, this supplement was featured on the Dr Oz show, where his team of dedicated professionals explained just how this new pill could help the body to use its excess fat stores AND block the ability to build new fat reserves whilst reducing the stress level cortisone.

So if you’re like me, and hold your excess weight around your middle, this could be the perfect solution.

Through the mechanisms of Hydroxycitric Acid or simply HCA: 1.

But, the reviews out there have been mixed with some people seeing good results and others seeing very little indeed. Could it be that this secret ingredient is nothing more than a marketing ploy, or are we being cheated by unscrupulous companies while we chase our dreams of a tighter, more toned body? I thought I’d check out GCE from my favorite store and see whether this really is a miracle weight loss supplement.

What is Garcinia Cambogia?

Before we get to the supplement, dosage, side effects and so on, I thought I’d include a little information about the source of the supplement. Garcinia Cambogia Extract is taken from the rind of the malaban tamarind fruit, a fruit native to South East Asia and India. It has been used medicinally and in food preparation in its native home for centuries, because it has been said to boast the following properties:

  • Souring agent, used in traditional Indian or South East Asian hot and sour curries[1]
  • Used for bowel problems and rheumatism[2]
  • Contains HCA (Hydroxycitric Acid) which has been under the spotlight for weight loss
  • Food preservative, coloring agent and curing agent
  • Used as a carmative to prevent or expel excess gas formed in the GI tract[3]

How is Garcinia Cambogia linked to weight loss?

Garcinia Cambogia is said to boost weight loss in two different ways. Firstly, it blocks the enzyme in the liver that is responsible for the default function of converting sugar and carbs to fat. So instead of the fat cells getting plumper, GCE ‘plugs’ the fat cells and directs any sugar and carbs to the energy stores to be burnt off. The body is processing less fat and is under less stress, so less cortisol (the belly fat-creating hormone) is produced. The second way that it works is by sending signals to the brain that release more serotonin, our happy hormone, and this happiness stops us craving stress foods like sugar, carbs and salty foods and could have a positive impact on appetite suppression. For more information about how Garcinia Cambogia works, please visit my review of the Dr Oz show.

About Garcinia Cambogia and its clinical studies

Several clinical studies have been undertaken to assess the efficacy of Garcinia Cambogia. At the moment the research is a little patchy and generally the medical community recommends more testing. I’ve written a longer article focused on Garcinia Cambogia research and clinical trials, but have included a summary right here for you:

  • In a four week trial[4], 150 obese subjects saw a significant, dose-dependent decrease in weight, LDL cholesterol and triglycerides, and an improvement in good cholesterol
  • In an eight week trial[5], 40 subjects saw an increase in weight loss against the placebo group
  • In a 12 week trial[6] with a reduced calorie diet, the group lost nearly three times as much weight as the placebo group
  • In a 4 week trial[7] with a reduced calorie diet, 89 mildly overweight women saw an increase in weight loss against the placebo group, but noted no discernible change to appetite
  • In an eight week trial[8] with a low fat diet and at least 64oz water consumption per day, 54 overweight subjects lost an average of 11.2lb per person
  • In an eight week trial[9] with a low fat diet and moderate (three times per week) exercise, 60 obese subjects saw a greater weight loss and reduction of appetite than the placebo group
  • In a 16 week trial[10] with a low fat diet and moderate exercise, all 39 subjects saw a reduction in belly fat and gained none of it when given a placebo for four weeks

Go to any medical site and they will be the first to say that the supplement and ingredients such as HCA need a ton more research. It’s the same with any new herbal supplement I guess. But the research that’s taken place to date is certainly encouraging.

Is It Trusted And Safe To Use?

Genuine Garcinia Cambogia has been noted to have been ‘well tolerated’ for up to 12 weeks in human trials. Whilst this is a little vague, it means that there are generally few adverse reactions. Be sure to read the ‘who should take Garcinia Cambogia’ section below, for a list of who should avoid the supplement.

Who Is Garcinia Cambogia For?

Being a natural supplement, there are few people that should avoid taking Garcinia Cambogia. However, until more research has been undertaken, it is recommended that the following people should avoid it, or use it under medical supervision:

  • Patients with diabetes (high blood sugar) or hypoglycemia (low blood sugar) should avoid the supplement
  • Patients taking any medication that affect blood sugar should use Garcinia Cambogia under medical supervision
  • Patients with a high risk or history of rhabdomyolysis (a potentially fatal disease involving the degeneration of skeletal muscle) should use Garcinia Cambogia under medical supervision
  • Patients taking statins, should exercise caution as the combined medicines may increase the risk of rhabdomyolysis
  • Those with Alzheimer’s or other forms of dementia should avoid Garcinia Cambogia because of the theoretical possibility of forming acetylcholine in the brain
  • Those trying to conceive, pregnant or breastfeeding should avoid until further scientific evidence can be undertaken

For my full article on Garcinia Cambogia, including dosage and potential side effects, please click here.

My Favorite Garcinia Supplement?

Once you’ve decided that you want to try Garcinia Cambogia, the most important element is finding the right supplier.

It’s a central nervous system stimulant and is one of the most used stimulants in the world.

I’m not pushing any particular brand as it can be difficult to know whether a brand has been replicated and is not in fact genuine. I know of at least two well-known doctors/celebs that have had to put out alerts to their users saying that they are NOT endorsing a particular brand of Garcinia Cambogia, as there are a lot of unscrupulous companies out there selling fake or poor quality goods. I strongly recommend this brand at Amazon. After buying from them, I received great customer support and they were able to provide proof that their Garcinia Cambogia had been tested by a third party lab.

In general, I would say:

  • Use a trusted brand or store like Amazon
  • Read online reviews about your chosen brand carefully
  • Check the small print and reviews if you choose a ‘money back guarantee’ option, make sure that people that have returned the product for whatever reason have actually got refunds
  • Choose a supplement that has at least 50% HCA
  • Choose a supplement that contains minerals such as potassium and chromium, as these seem to have better reviews online
  • Choose a supplement that contains at least 600mg per day
  • Choose a supplement free from fillers or binders

Taking Garcinia Cambogia

I chose a supplement to try from my local and trusted health food store, and took 500mg three times per day.

**ULTRA-IMPORTANT** It’s critical that you take the supplements on an empty stomach, around 30-60 minutes before a meal. Food will interact with the supplement and reduce its efficacy. Also, I’m not sure of the science behind this, but I recall one study saw fewer results because the subjects were on a high fiber diet. Somehow that interfered, so eat a balanced healthy diet rich in vegetables, fruit, lean meats and good fats.

I took a supplement that also contained potassium, because I trusted Dr Oz!! I didn’t take any additional extracts as I wanted to see what this supplement did on its own.

So I took the pills three times a day, on an empty stomach. Unlike some supplements I’ve taken, I had no nausea or restlessness, you know like those buzzy caffeine pills. After drinking each one with a big glass of water, it’s common sense that an hour later you’ll be less hungry than you were, but my appetite was definitely more satiated than if I’d just had water.

The results were pretty much from day one, I was less hungry and ate slightly smaller meals, but the biggest effect I saw was in the type of food I wanted and the impact on my snacking. I know that my excess weight is down to my continual grazing, I eat pretty healthy but I can’t sleep unless I’ve had a full carb-loaded meal. And – ladies – at THAT time of the month I have an insatiable appetite for candy, chocolate, crisps, crackers…you name it! But in the three months that I took Garcinia Cambogia, my cravings all but disappeared. I ate when I was hungry (such a novelty for me, usually eating without even being aware of it) and saw the weight come off almost instantly.

I’ll be honest, we’re not talking total body transformations or anything. But I had stubborn belly fat that all types of exercise and diet had failed to get rid of for good. I guess I was carrying an extra 10lb over my ideal weight, and the majority of that was round my stomach. Garcinia Cambogia seemed to target that fat exclusively, which was a win-win for me as I didn’t want to lose any from my bust or butt. So in three months I lost around 9lb, but it was all from where I wanted it to go, and with no discernible change to my diet or exercise regime. I’m pretty fit so kept up the jogging and yoga, and it all seemed to work in harmony! I’ve now got a tighter waistline and am eating ‘mindfully’ for the first time in a hundred years!!

The million dollar question: Does Garcinia Cambogia work?

For me, it definitely worked. I saw reduced cravings to snack, and when I did eat, I was fuller faster, and on better quality foods. During my time of the month, I had little to no cravings. In fact, one time I went to the cinema and usually gorge on popcorn, but I only dipped in and out of this time (my husband was cursing me as he ended up eating it all!).

That said, it will only work if it’s a genuine product with a minimum 50% HCA. There are a lot of stores or vendors out there selling inferior products, which is why, in my mind, some people aren’t seeing the results they hoped.

What’s great about Garcinia Cambogia?

  • Natural supplement based on fruit used commonly for centuries
  • Helps curb cravings for sugar/salt/carbohydrates
  • Can boost weight loss, best used in conjunction with a healthy diet and moderate activity
  • No horrible side effects like nausea or headaches
  • Endorsed by doctors, models and celebrities
  • Cheap, compared to many supplements

Anything not so great?

  • Some people have seen minimal results – I say you can’t eat everything and expect to lose weight!
  • Some people have seen no results – I keep saying it, but check you’re buying from a reputable source and that the supplement contains at least 50% HCA
  • Can’t be used by those with blood sugar issues (see my full Side Effects of Garcinia Cambogia report)

What others are saying about Garcinia Cambogia?

I’ve researched many sources of Garcinia Cambogia users to bring you a consolidation of the most frequent opinions.

Here are the things a garcinia cambogia brand must have to be considered safe and effective: The label on the bottle must have "Garcinia Cambogia," "GCE," or "HCA." It must have at least 50% pure HCA It must provide a dosage between 500-1000mg in every capsule The list of ingredients must be labeled with no fillers and artificial ingredients BodyBloom Cambogia The Bestselling Garcinia Cambogia Meeting all the criteria set in the industry for a genuinely authentic garcinia cambogia supplement, BodyBloom Garcinia Cambogia is one of the national best sellers!

In summary, there have been a lot of people ripped off and for them, they’ve lost money and not seen any results. For those that have bought reputable brands, they’ve seen moderate results which have been optimized by a healthy diet and moderate activity. Here are the views:

  • “I dropped from 13.5% to 11% body fat in time for my beauty show.”
  • “I have been taking for 2 weeks and have lost 8lbs, I love it!”
  • “I have been taking Garcinia Cambogia for 2 months and have lost 10lbs.”
  • “I have been taking it for two weeks and don’t see an extraordinary change, just 3lbs in two weeks.”
  • “After 1 week, I was surprised by the dramatic results…my energy levels were up and I wasn’t even hungry…after the fifth week my results were shocking. I lost an unbelievable 23lbs.”
  • “I’ve been taking it for a week and gained 3lbs!”
  • “Never buy from a site that appeared 1 hour after the Dr Oz show.”
  • “Took for a month and no weight loss”
  • “I purchased mine at GNC after talking to the sales person. She said her husband lost 60 lbs but she has only lost 10, but she admitted he works out more.”

My opinion: A summary review of Garcinia Cambogia

It’s not often you can find something that helps you lose weight without changing your diet or exercise habits, but Garcinia Cambogia seems to do just that. I made no changes but saw a drop of 9lb over my trial period, I’m now down to my ideal weight and have lost it all from my belly. I bought from a store I trusted, and went for a supplement with over 50% HCA, and it really worked, particularly in curbing my grazing and snacking. As with any diet supplement, there will be rogue dealers out there so always check reviews before buying online, use recommended products or buy via your trusted store. Here’s to the body you’ve always wanted!

[4] Girola M, De Bernardi M, Contos S, et al. Dose effect in lipid-lowering activity of a new dietary integrator (chitosan), Garcinia combogia extract and chrome. Acta Toxicol Ther . 1996;17(1):25-40.

[5] Soni MG, Burdock GA, Preuss HG, Stohs SJ, Ohia SE, Bagchi D. Safety assessment of (-)-hydroxycitric acid and Super CitriMax, a novel calcium/potassium salt. Food Chem Toxicol . 2004;42(9):1513-1529.

[6] Thom E. A randomized, double-blind, placebo-controlled trial of a new weight-reducing agent of natural origin. J Int Med Res . 2000;28(5):229-233.

[7] Mattes RD, Bormann L. Effects of (-)-hydroxycitric acid on appetitive variables. Physiol Behav . 2000;71(1-2):87-94.

[8] Lau FC, Bagchi M, Sen C, Roy S, Bagchi D. Nutrigenomic analysis of diet-gene interactions on functional supplements for weight management. Curr Genomics . 2008;9(4):239-251

[9] Lau FC, Bagchi M, Sen C, Roy S, Bagchi D. Nutrigenomic analysis of diet-gene interactions on functional supplements for weight management. Curr Genomics . 2008;9(4):239-251

[10] Hayamizu K, Ishii Y, Kaneko I, et al. Effects of Garcinia cambogia (hydroxycitric acid) on visceral fat accumulation: A double-blind, randomized, placebo-controlled trial. CurrTher Res Clin Exp . 2003;64(8):551-567.