The original garcinia cambogia extract

The original garcinia cambogia extract
By the end of the 8 week period, the placebo group had lost an average of 3 pounds.

Garcinia Cambogia: Safe for Weight Loss?

In this Article

In this Article

In this Article

Garcinia cambogia, a tropical fruit also known as the Malabar tamarind, is a popular weight-loss supplement. People say it blocks your body's ability to make fat and it puts the brakes on your appetite. It could help keep blood sugar and cholesterol levels in check, too. You'll find it in bottles on the shelf at the store as well as mixed with other ingredients in diet products.

Does it live up to its hype? Maybe a little, but it might not be worth it.

How It Works

The active ingredient in the fruit's rind, hydroxycitric acid, or HCA, has boosted fat-burning and cut back appetite in studies. It appears to block an enzyme called citrate lyase, which your body uses to make fat. It also raises levels of the brain chemical serotonin, which may make you feel less hungry.

But actual weight loss results aren't impressive. A review published in the Journal of Obesityfound that people who took garcinia cambogia in studies lost about 2 pounds more than people who didn't take it. The reviewers couldn't say for sure that the weight loss was because of the supplement. It could have been from the lower-calorie diet and exercise programs the people in the studies typically followed. Better studies are needed to find out if HCA really helps people lose a lot of weight and keep it off.

Type 2 Diabetes and High Cholesterol

Garcinia cambogia may make it easier for your body to use glucose, the sugar your cells need for energy. Mice that got garcinia cambogia in one study had lower insulin levels than mice that didn't. That's another reason, besides weight loss, that people with diabetes are interested in it. However, if you're taking garcinia cambogia along with a medication to control your blood sugar, your glucose could get dangerously low.

Some research has found that garcinia cambogia can also improve cholesterol levels, lowering triglycerides and LDL (the "bad" cholesterol) and raising HDL (the "good" cholesterol). But you shouldn't use it if you're already on a prescription for your cholesterol.

Possible Side Effects

When you take garcinia cambogia, you might get:

In 2009, the Food and Drug Administration warned everyone to stop using a weight-loss product that contained garcinia cambogia because some people taking it got serious liver problems. The product had other ingredients, too, so it's not clear that garcinia cambogia was to blame. While some research suggests the supplement is safe for your liver, other research says no.

Garcinia cambogia may interact badly with:

You definitely don't want to use it when you're pregnant or nursing, or if you have kidney or liver problems.

The cravings decrease approaches they have are very powerful.

It is possible that manic symptoms may emerge as a side effect.

To Buy or Not to Buy

Since study results are mixed, you should talk with your doctor to help you decide if taking garcinia cambogia is a good idea. Even if it's safe, it may not help you lose much weight. It's probably wiser to spend your money on healthy food or an exercise DVD.

Onakpoya, I. Journal of Obesity, 2011.

NYU Langone Medical Center: "Weight Loss Aids."

Byrne, S. Consumer Reports, March 24, 2014.

Wielinga, P.Y. American Journal of Physiology, June 1, 2005.

Leonhardt, M. Nutrition, October 2004.

Hayamizu, K. Fitoterapia, April 2003.

Preuss, H. Nutrition Research, January 2004.

Preuss, H. Diabetes, Obesity and Metabolism, May 2004.

Preuss, H. International Journal of Clinical Pharmacology Research, February 2005. "Garcinia (hydroxycitric acid)."

Kim, Y. World Journal of Gastroenterology, Aug. 7, 2013.

Stohs, S. Toxicology Mechanisms and Methods, November 2010.

Clouatre, D. World Journal of Gastroenterology, Nov. 28, 2013.

Marquez, F. Critical Reviews in Food Science and Nutrition, Issue 7, 2012.

Medscape: "Leukotriene Receptor Antagonists."

The Truth About Garcinia Cambogia

If you ask me, there's really only one way to lose weight and keep it off, and that's to adopt a healthy lifestyle. That includes eating nutritious meals and exercising daily.

But there are plenty of marketers out there would vehemently disagree – because magic pills make money. Acai berry, green tea extract and capsaicin all had their time in the spotlight.

But, let's explore a supplement that has exploded on the weight loss scene more recently: Garcinia cambogia.

Garcinia cambogia is a small, pumpkin-shaped fruit. You may know it as tamarind. The extract of the fruit is called hydroxycitric acid, and that is what the "magic pills" are made from. But do they work? [9 Meal Schedules: When to Eat to Lose Weight]

Let's explore the research:

1998 study published in the Journal of the American Medical Association: After a 12-week randomized, double-blind study of overweight men and women, researchers concluded that Garcinia cambogia did not produce significant weight or fat loss above the placebo.

2013 review in the journal Complementary Theories in Medicine: Researchers evaluated clinical trials that used plant extracts as potential treatment for obesity, and found that the evidence was not convincing in most cases.

These special offers are valid only until the end of this month or while promotional stocks last.

Garcinia (hydroxycitric acid) Scientific Name(s): Garcinia cambogia (Gaertn.) Desr.

One exception was a combination of Garcinia cambogia taken with another herb called Gymnema sylvestre, which showed a slight increase in weight loss results. It's a glimmer of hope, but surely, more research needs to be done on the subject.

2005 study in the journal Food and Chemical Toxicology: Researchers tested a high dose of Garcinia cambogia extract on obese male rats. The good news? The rats lost weight! The bad news? Extremely high doses seemed to cause testicular atrophy and toxicity. Yikes!

If you do decide to hop on the latest bandwagon, whether it is Garcinia cambogia or some other plant-based extract, proceed with caution. If you're talking any prescription medications, talk to your doctor before adding any herbal supplement. There may be dangerous interactions. And as researchers saw in the 2005 study on rats, there may be consequences to taking large doses. [Related: Garcinia Cambogia Supplement Often Lacks Active Ingredient, Study Finds]

Until we have more research to draw from, we can't know what is truly safe.

Healthy Bites appears weekly on LiveScience. Deborah Herlax Enos is a certified nutritionist and a health coach and weight loss expert in the Seattle area with more than 20 years of experience. Read more tips on her blog, Health in a Hurry!

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